Axl-IN-10 [2487649-61-4]

MedChem Express

Axl-IN-10 [2487649-61-4]

10

2487649-61-4

Research Use Only

C27H25N7O2

479.53

Axl-IN-10 (Example 1) is a potent AXL inhibitor, with an IC50 of 5 nM. Axl-IN-10 has excellent transmembrane properties.Axl-IN-10 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-10 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1].

CN1C=C(C2=C1N=CN=C2N)C3=CC=C(C=C3)NC(C4=C5CCCCN5N(C4=O)C6=CC=CC=C6)=O

12131703