AXL-IN-14 [2947506-65-0]
HY-152075
CAS Number2947506-65-0
Product group Chemicals
Molecular Weight566.55
Overview
- SupplierMedChem Express
- Product NameAXL-IN-14 [2947506-65-0]
- Delivery Days Customer10
- CAS Number2947506-65-0
- CertificationResearch Use Only
- Molecular FormulaC32H24F2N4O4
- Molecular Weight566.55
- Scientific DescriptionAXL-IN-14 is a potent and orally active AXL inhibitor with an IC50 value of 0.8 nM. AXL-IN-14 inhibits Gas6/AXL-mediated cell migration and invasion. AXL-IN-14 decreases the expression of p-AXL and p-AKT proteins. AXL-IN-14 shows anti-tumor activity[1].
- SMILESFC1=CC(NC(C2=CN(C=C(C2=O)C3=CC=C(C=C3)F)C(C)C)=O)=CC=C1OC4=CC=NC5=C4OC6=CC=CC=C6N5
- UNSPSC12352200