AZ 628

MedChem Express

AZ 628 [878739-06-1]

10

878739-06-1

99.85

C27H25N5O2

451.52

AZ 628 is a pan-Raf kinase inhibitor with IC 50 s of 105, 34 and 29 nM for B-Raf , B-RafV600E , and c-Raf-1 , respectively.

O=C1N(C)C=NC2=C1C=C(C=C2)NC3=C(C)C=CC(NC(C4=CC(C(C#N)(C)C)=CC=C4)=O)=C3

-20°C,2°C to 8°C

12352200