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AZ084 [929300-19-6]

HY-119217
MedChem Express
CAS Number929300-19-6
Product group Chemicals
Estimated Purity99.65
Molecular Weight434.57
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AZ084 [929300-19-6]
  • Delivery Days Customer
    10
  • CAS Number
    929300-19-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C26H34N4O2
  • Molecular Weight
    434.57
  • Scientific Description
    AZ084 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a Ki of 0.9 nM. Has potential to treat asthma[1]. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche (PMN) and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer[1][2].
  • SMILES
    O=C(C1=NC=C(N)C=C1)N2CCC3(CCN(CC4=C5CC(C)(C)OC5=CC=C4)CC3)CC2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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