AZ6102

MedChem Express

AZ6102 [1645286-75-4]

10

1645286-75-4

Research Use Only

99.65

C25H28N6O

428.53

AZ6102 is a potent dual TNKS1 and TNKS2 inhibitor, with IC50s of 3 nM and 1 nM, respectively, and alao has 100-fold selectivity against other PARP family enzymes, with IC50s of 2.0 microM, 0.5 microM, and >3 microM, for PARP1, PARP2, and PARP6, respectively.

O=C1C2=C(N(C)C=C2)N=C(C3=CC=C(C4=C(C)C=C(N5C[C@@H](C)N[C@@H](C)C5)N=C4)C=C3)N1

-20°C,2°C to 8°C

12352200