AZD-1480 [935666-88-9]

TargetMol Chemicals

AZD-1480 [935666-88-9]

4

935666-88-9

Chemical

Research Use Only

AZD-1480

98.55%

C14H14ClFN8

348.77

AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera, Primary Myelofibrosis (PMF), and Essential Thrombocythaemia Myelofibrosis.

3 years

C[C@H](Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1

-20°C

12352200