AZD-1897 [1204181-93-0]

TargetMol Chemicals

AZD-1897 [1204181-93-0]

72

Chemical

Research Use Only

AZD-1897

C18H23N3O3S

361.46

AZD-1897 is an ATP-competitive pan-PIM inhibitor. When combined with the Akt inhibitor AZD5363, AML cells from putative leukaemia stem cells incur a reduction in levels of the anti-apoptotic protein MCL1. The combination of PIM and Akt inhibition holds promise for the treatment of AML.

3 years

C(\C1=C(C(OC(C)C)=CC=C1)N2C[C@H](N)CCC2)=C/3\SC(=O)NC3=O

-20°C

12352200