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ProductsBack/AZD-26 [1357158-81-6]
Chemical Structure
Chemical Structure
Chemical Structure

AZD-26 [1357158-81-6]

Research Use Only
SYN-1160
SYNkinase
CAS Number1357158-81-6
Product group Chemicals
Estimated Purity>95%
Molecular Weight343.4
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Overview

  • Supplier
    SYNkinase
  • Product Name
    AZD-26 [1357158-81-6]
  • Delivery Days Customer
    10
  • CAS Number
    1357158-81-6
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C22H21N3O
  • Molecular Weight
    343.4
  • Scientific Description
    AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01microM to 10microM after 24 hour exposure in several rat and human cell models. Likewise AZD-25 used at 100-200mg/kg also inhibited AKT phosphorylation and subsequent activation. - Chemical. CAS: 1357158-81-6. Formula: C22H21N3O. MW: 343.4. AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01microM to 10microM after 24 hour exposure in several rat and human cell models. Likewise AZD-25 used at 100-200mg/kg also inhibited AKT phosphorylation and subsequent activation.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    51202000