AZD-5672 [780750-65-4]

MedChem Express

AZD-5672 [780750-65-4]

5

780750-65-4

Research Use Only

95.74

C32H38F2N2O5S2

632.78

AZD-5672 is an orally active, potent, and selective CCR5 antagonist (IC50=0.32 nM). AZD-5672 shows moderate activity against the hERG ion channel (binding IC50=7.3 microM). AZD5672 is a substrate of human P-gp, and inhibits P-gp-mediated digoxin transport (IC50=32 microM). AZD-5672 can be used for the research of rheumatoid arthritis[1][2][3].

O=C(N(C1CCN(CC[C@@H](C2=CC(F)=CC(F)=C2)C3=CC=C(S(=O)(C)=O)C=C3)CC1)CC)CC4=CC=C(S(=O)(C)=O)C=C4

-20°C,2°C to 8°C

12352200