AZD-8835

AbMole BioScience

AZD-8835

9

1620576-64-8

Research Use Only

>98.0%

C22H31N9O3

469.54

AZD8835 ia a novel mixed inhibitor of PI3Kalfa and PI3Kdelta with IC50 of 6.2 nM and 5.7 nM, respectively, also with selectivity against PI3Kbèta (IC50=431 nM) and PI3Kgamma (IC50=90 nM).

CC[N]1N=C(N=C1C2=CN=C(N)C(=N2)C3=NN=C(O3)C(C)(C)C)C4CCN(CC4)C(=O)CCO

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