AZD0156

MedChem Express

AZD0156 [1821428-35-6]

10

1821428-35-6

Research Use Only

99.83

C26H31N5O3

461.56

AZD0156 is a potent, selective and orally active ATM inhibitor with an IC 50 of 0.58 nM. AZD0156 inhibits the ATM -mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis [1] .

O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3

-20°C,2°C to 8°C

12352200