AZD1080

MedChem Express

AZD1080 [612487-72-6]

10

612487-72-6

99.46

C19H18N4O2

334.37

AZD1080 is a potent and selective GSK3 inhibitor. AZD1080 inhibits recombinant human GSK3alpha and GSK3beta with pK i ( IC 50 ) of 8.2 (6.9 nM) and 7.5 (31 nM), respectively.

OC(N1)=C(C2=CC=C(CN3CCOCC3)C=N2)C4=C1C=CC(C#N)=C4

-20°C,2°C to 8°C

12352200