AZD1283 [919351-41-0]

TargetMol Chemicals

AZD1283 [919351-41-0]

9

919351-41-0

Chemical

Research Use Only

AZD1283

98.37%

C23H26N4O5S

470.54

AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 and 10 microg/kg/min, respectively. The doses induced the increase in bleeding time at 33 and 100 microg/kg/min for 3- and 13-fold, respectively. Thus, the therapeutic index (TI) was ≥10 for both compounds.

3 years

CCOC(=O)c1cc(C#N)c(nc1C)N1CCC(CC1)C(=O)NS(=O)(=O)Cc1ccccc1

-20°C

12352200