AZD1390

AbMole BioScience

AZD1390

9

2089288-03-7

Chemical

Research Use Only

C27H32FN5O2

477.57

AZD1390 is currently the most effective and highly selective ATM inhibitor with an IC50 of 0.78 nM, oral activity and the ability to cross the blood-brain barrier. In vivo, AZD1390 combined with radiotherapy effectively inhibited tumor growth.

CC(C)N1C(=O)N(C)C2=C1C3=CC(=C(F)C=C3N=C2)C4=CC=C(OCCCN5CCCCC5)N=C4

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