AZD3759 hydrochloride [1626387-81-2]

TargetMol Chemicals

AZD3759 hydrochloride

4

1626387-81-2

Chemical

Research Use Only

AZD3759 hydrochloride

99.41%

C22H24Cl2FN5O3

496.36

AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).

3 years

C[C@@H]1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C.Cl

-20°C

12352200