AZD7325 (Standard) [942437-37-8]

MedChem Express

AZD7325 (Standard) [942437-37-8]

999

Research Use Only

AZD7325 (Standard) is the analytical standard of AZD7325. This product is intended for research and analytical applications. AZD7325 is a potent and orally active partial selective PAM of GABAAalpha2 and Aalpha3 receptor (Ki=0.3 and 1.3 nM, respectively), and has less antagonistic efficacy at the Aalpha1 and Aalpha5 receptor subtypes[1][4]. AZD7325 is a moderate CYP1A2 and a potent CYP3A4 inducer in vitro[2]. AZD7325 has the potential for the investigation of anxiety and dravet syndrome[3]. PAM: positive allosteric modulator.

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