Azide-C2-SS-C2-biotin [1620523-64-9]

MedChem Express

Azide-C2-SS-C2-biotin [1620523-64-9]

10

1620523-64-9

Research Use Only

99.84

C14H24N6O2S3

404.57

Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(NCCSSCCN=[N+]=[N-])CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

-20°C,2°C to 8°C

41115800