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ProductsBack/Azide-PEG8-Val-Cit-PAB-MMAE
Chemical Structure
Chemical Structure
Chemical Structure

Azide-PEG8-Val-Cit-PAB-MMAE

Research Use Only
82277
BPS Bioscience
Estimated Purity≥98%
Product group Chemicals
Molecular Weight1573.0 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Azide-PEG8-Val-Cit-PAB-MMAE
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C77H129N13O21
  • Molecular Weight
    1573.0 Da
  • Scientific Description
    Azide-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker which contains an azide, a PEG spacer, a Val-Cit dipeptide, a PAB group, and an MMAE warhead. The azide is free to participate in click chemistry with terminal alkynes or strained cyclooctynes such as DBCO or BCN. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient MMAE payload delivery via an elimination mechanism within the PAB structure.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200