Azido-PEG1-Val-Cit-PABC-PNP

MedChem Express

Azido-PEG1-Val-Cit-PABC-PNP

10

Research Use Only

C30H39N9O10

685.68

Azido-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(NC1=CC=C(COC(OC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCN=[N+]=[N-])=O)=O

41115800