Azido-PEG3-Val-Cit-PAB-OH [2055024-65-0]

MedChem Express

Azido-PEG3-Val-Cit-PAB-OH [2055024-65-0]

10

2055024-65-0

Research Use Only

C27H44N8O8

608.69

Azido-PEG3-Val-Cit-PAB-OH is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(N)[C@H](CCCNC(N)=O)N(C([C@H](C(C)C)NC(CCOCCOCCOCCN=[N+]=[N-])=O)=O)C1=CC=C(CO)C=C1

41115800