Azido-PEG4-Val-Cit-PAB-MMAE [1869126-64-6]

MedChem Express

Azido-PEG4-Val-Cit-PAB-MMAE [1869126-64-6]

10

1869126-64-6

Research Use Only

99.43

C69H113N13O17

1396.71

Azido-PEG4-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH[1]. Azido-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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-20°C

41115800