Azido-PEG5-CH2CO2H [217180-81-9]

MedChem Express

Azido-PEG5-CH2CO2H [217180-81-9]

5

217180-81-9

Research Use Only

98.88

C12H23N3O7

321.33

Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(O)COCCOCCOCCOCCOCCN=[N+]=[N-]

-20°C

41115800