Azidoethyl-SS-propionic NHS ester [2243566-44-9]

MedChem Express

Azidoethyl-SS-propionic NHS ester [2243566-44-9]

10

2243566-44-9

Research Use Only

C9H12N4O4S2

304.35

Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(ON1C(CCC1=O)=O)CCSSCCN=[N+]=[N-]

41115800