AZT triphosphate [92586-35-1]

MedChem Express

AZT triphosphate [92586-35-1]

10

92586-35-1

Research Use Only

C10H16N5O13P3

507.18

AZT triphosphate (3-Azido-3-deoxythymidine-5-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate also inhibits the DNA polymerase of HBV. AZT triphosphate activates the mitochondria-mediated apoptosis pathway[1][2][3].

O=C1NC(N([C@@H](C[C@@H]2N=[N+]=[N-])O[C@@H]2COP(OP(O)(OP(O)(O)=O)=O)(O)=O)C=C1C)=O

12352200