AZT triphosphate (TEA)

MedChem Express

AZT triphosphate (TEA)

10

Research Use Only

C10H16N5O13P3.xC6H15N

AZT triphosphate (3-Azido-3-deoxythymidine-5-triphosphate) TEA is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TEA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TEA also inhibits the DNA polymerase of HBV. AZT triphosphate TEA activates the mitochondria-mediated apoptosis pathway[1][2][3].

O=C1NC(N([C@@H](C[C@@H]2N=[N+]=[N-])O[C@@H]2COP(OP(O)(OP(O)(O)=O)=O)(O)=O)C=C1C)=O.CCN(CC)CC.[x]

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