Azvudine
HY-19314
CAS Number1011529-10-4
Product group Chemicals
Estimated Purity99.79
Molecular Weight286.22
Overview
- SupplierMedChem Express
- Product NameAzvudine [1011529-10-4]
- Delivery Days Customer5
- CAS Number1011529-10-4
- CertificationResearch Use Only
- Estimated Purity99.79
- Molecular FormulaC9H11FN6O4
- Molecular Weight286.22
- Scientific DescriptionAzvudine (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV , HBV and HCV . Azvudine exerts highly potent inhibition on HIV-1 (EC 50 s ranging from 0.03 to 6.92 nM) and HIV-2 (EC 50 s ranging from 0.018 to 0.025 nM). Azvudine inhibits NRTI-resistant viral strains [1] . Azvudine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO[C@@H]1[C@](CO)(N=[N+]=[N-])O[C@@H](N2C(N=C(N)C=C2)=O)[C@H]1F
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200