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ProductsBack/b-AP15 (NSC-687852) [1009817-63-3]

b-AP15 (NSC-687852) [1009817-63-3]

27701
BPS Bioscience
CAS Number1009817-63-3
Product group Chemicals
Estimated Purity≥98%
Molecular Weight419.4 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    b-AP15 (NSC-687852)
  • Delivery Days Customer
    7
  • CAS Number
    1009817-63-3
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C22H17N3O6
  • Molecular Weight
    419.4 Da
  • Scientific Description
    Blocks 26S proteasome activity by inhibiting the ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) activities of the 19S regulatory subunit without affecting the catalytic activity of the 20S core subunit. b-AP15 displays several differences to bortezomib including insensitivity to over-expression of the anti-apoptotic mediator Bcl-2 and anti-tumor activity in four solid tumor models.
  • UNSPSC
    51202000

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