CgoaEGY7R7OEWz2NAAAAAI_C4Cs922.png
CgoaEGY7R7OEWz2NAAAAAI_C4Cs922.png
B I09
T14847
CAS Number1607803-67-7
Product group Chemicals
Molecular Weight303.31
Overview
- SupplierTargetMol Chemicals
- Product NameB I09
- Delivery Days Customer4
- CAS Number1607803-67-7
- Category SupplierChemical
- Chemical NameB I09
- Molecular FormulaC16H17NO5
- Molecular Weight303.31
- Scientific DescriptionB I09, an IRE-1 RNase inhibitor with an IC50 of 1230 nM, inhibits splicing of XBP1 mRNA in human WaC3 cells and expression of xbp-1 in LPS-stimulated B cells. B I09 can be used to simulate the defects of XBP-1 in CLL cells., an IRE-1 RNase inhibitor with an IC50 of 1230 nM, inhibits splicing of XBP1 mRNA in human WaC3 cells and expression of xbp-1 in LPS-stimulated B cells. B I09 can be used to simulate the defects of XBP-1 in CLL cells., an IRE-1 RNase inhibitor with an IC50 of 1230 nM, inhibits splicing of XBP1 mRNA in human WaC3 cells and expression of xbp-1 in LPS-stimulated B cells. B I09 can be used to simulate the defects of XBP-1 in CLL cells.
- Shelf life instruction3 years
- SMILESOC=1C(=C2C(C3=C(C(=O)O2)CNCC3)=CC1)C4OCCCO4
- Storage Instruction-20°
- UNSPSC12352200
References
- Ranatunga S, Tang CH, Kang CW, et al. Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity. J Med Chem. 2014;57(10):4289-4301.Read more