B-Raf IN 11 [918504-27-5]

MedChem Express

B-Raf IN 11 [918504-27-5]

10

918504-27-5

Research Use Only

99.55

C17H14BrF2N3O3S

458.28

B-Raf IN 11 (ZINC72115182) is a selective B-RafV600E inhibitor (IC50=76 nM), shows selectivity for B-RafV600E over B-RafWT with selectivity of 3.1-fold. B-Raf IN 11 can be used in colorectal cancer research[1]

FC1=C(C(C2=CNC3=NC=C(Br)C=C32)=O)C(F)=C(NS(=O)(CCC)=O)C=C1

-20°C,2°C to 8°C

12352200