B-Raf IN 8 [1215313-19-1]
HY-147853
CAS Number1215313-19-1
Product group Chemicals
Molecular Weight307.35
Overview
- SupplierMedChem Express
- Product NameB-Raf IN 8 [1215313-19-1]
- Delivery Days Customer10
- CAS Number1215313-19-1
- CertificationResearch Use Only
- Molecular FormulaC18H17N3O2
- Molecular Weight307.35
- Scientific DescriptionB-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 microM[1].
- SMILESO=C1CCC(C2=CC=C(/N=C/C3=CC=C(OC)C=C3)C=C2)=NN1
- UNSPSC12131703