B-Raf IN 8 [1215313-19-1]

MedChem Express

B-Raf IN 8 [1215313-19-1]

10

1215313-19-1

Research Use Only

C18H17N3O2

307.35

B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 microM[1].

O=C1CCC(C2=CC=C(/N=C/C3=CC=C(OC)C=C3)C=C2)=NN1

12131703