B022 [1202764-53-1]

MedChem Express

B022 [1202764-53-1]

9

1202764-53-1

Research Use Only

99.76

C19H16ClN5OS

397.88

B022 is a potent and selective NF-kappaB-inducing kinase (NIK) inhibitor (Ki of 4.2 nM; IC50=15.1 nM). B022 protects liver from toxin-induced inflammation, oxidative stress, and injury[1][2]. B022 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CC(C1=NC=CS1)(C#CC2=CC3=C(CCN3C4=NC(N)=NC=C4Cl)C=C2)O

-20°C,2°C to 8°C

12352200