B026 [2379416-48-3]
HY-147261
CAS Number2379416-48-3
Product group Chemicals
Molecular Weight557.50
Overview
- SupplierMedChem Express
- Product NameB026 [2379416-48-3]
- Delivery Days Customer10
- CAS Number2379416-48-3
- CertificationResearch Use Only
- Molecular FormulaC27H23F4N5O4
- Molecular Weight557.50
- Scientific DescriptionB026 is a selective, potent, orally active p300/CBP histone acetyltransferase (HAT) inhibitor with IC50 values of 1.8 nM and 9.5 nM for p300 and CBP enzyme, respectively. B026 has anticancer activity for androgen receptor-positive (AR+) prostate cancer cell lines[1].
- SMILESO=C1[C@@]2(NC(N1CC(N3[C@@H](COC4=CC=C(F)C=C4C3)C(F)(F)F)=O)=O)C5=CC=C(C6=CN(N=C6)C)C=C5CC2
- UNSPSC12131703