B7-H2/ICOSLG, Cynomolgus (HEK293, Fc)
HY-P76394
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameB7-H2/ICOSLG, Cynomolgus (HEK293, Fc)
- Delivery Days Customer10
- CertificationResearch Use Only
- Gene ID102132485
- Target nameICOSLG
- Target descriptioninducible T cell costimulator ligand
- Target synonymsICOS ligand
- Scientific DescriptionB7-H2 is the ligand of Inducible Costimulator, was a ligand for CD28 and CTLA-4 in human, whereas these interactions were not conserved in mouse. B7-H2 interacted with CD28 in a non-overlapping domain. B7-H2 costimulation via CD28 induced survival factor Bcl-xL, downregulated cell cycle inhibitor p27kip1 and triggered signaling cascade of ERK and AKT kinases-dependent pathways[1][2]. B7-H2/ICOSLG Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived B7-H2/ICOSLG protein, expressed by HEK293 , with C-hFc labeled tag.
- UNSPSC41116100
- SpeciesPrimate