BACE2 antibody [C1C3]

GeneTex

BACE2 antibody [C1C3]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.83 mg/ml

Unconjugated

Liquid

BACE2

beta-secretase 2

56 kDa aspartic-like protease; AEPLC; ALP56; ASP1; ASP21; aspartyl protease 1; BAE2; beta-secretase 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; beta-site APP-cleaving enzyme 2; CDA13; CEAP1; Down syndrome region aspartic protease; DRAP; memapsin-1; membrane-associated aspartic protease 1; SLCO3A1/BACE2 fusion; theta-secretase; transmembrane aspartic proteinase Asp1

Rabbit

IgG

Beta-secretase 2

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimers disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the Down critical region of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203