Western blot analysis of extracts from 293 cells using BAD(Ab-112) Antibody and the same antibody preincubated with blocking peptide.
Western blot analysis of extracts from 293 cells using BAD(Ab-112) Antibody and the same antibody preincubated with blocking peptide.
Bad (Ab-112) Antibody
CSB-PA103572
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBad
Overview
- SupplierCusabio
- Product NameBad (Ab-112) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID12015
- Target nameBad
- Target descriptionBCL2-associated agonist of cell death
- Target synonymsAI325008; Bbc2; bcl2 antagonist of cell death; bcl2-associated agonist of cell death; bcl-2-binding component 6; bcl-xL/Bcl-2-associated death promoter
- HostRabbit
- IsotypeIgG
- Protein IDQ61337
- Protein NameBcl2-associated agonist of cell death
- Scientific DescriptionThe protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. Zhang B, et al. (2004). Mol Cell Biol.24 (14): 6205-6214. Rice PL, et al. (2003). Cancer Res.63 (3): 616-620. Wang XQ, et al. (2001). J Biol Chem.276 (48): 44504-44511.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203