BAF53A antibody

GeneTex

BAF53A antibody

7

WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Research Use Only

Polyclonal

Unconjugated

Liquid

ACTL6A

actin like 6A

53 kDa BRG1-associated factor A; actin-like protein 6A; actin-related protein 4; actin-related protein Baf53a; ACTL6; Arp4; arpNbeta; ARPN-BETA; BAF complex 53 kDa subunit; BAF53; BAF53A; BRG1-associated factor 53A; hArpN beta; INO80 complex subunit K; INO80K; SMARCN1

Rabbit

IgG

Actin-like protein 6A

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203