BAFF Receptor peptide
GTX26086
Overview
- SupplierGeneTex
- Product NameBAFF Receptor peptide
- Delivery Days Customer9
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- Concentration0.20 mg/ml
- ConjugateUnconjugated
- Scientific DescriptionMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kappaB and c-jun N terminal kinase.
- Storage Instruction-20°C
- UNSPSC12352202