Bafilomycin B1 [88899-56-3]

Bioss

Bafilomycin B1 [88899-56-3]

16

88899-56-3

Research Use Only

Unconjugated

>97%

C44H65NO13

815.9

Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antitrypanosomal and antileishmanial compound. Phytotoxic. Influences the cell wall biosynthesis of Asp. niger.

[H][C@@]1(OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C\C(C)=C\C=C/[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](OC(=O)\C=C\C(=O)NC2=C(O)CCC2=O)[C@H](C)C(O1)C(C)C

-20°C

12161600