Bafilomycin C1 [88979-61-7]

BioViotica

Bafilomycin C1 [88979-61-7]

10

6.1

88979-61-7

Research Use Only

>98%

Danger,Excepted quantity

C39H60O12

720.9

Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, insecticidal and anthelmintic. Antifungal activity, especially against C. albicans. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer. Cytotoxic activity against SMMC7721 HCC cells. Potential candidate for hepatic carcinoma chemotherapy. - Chemical. CAS: 88979-61-7. Formula: C39H60O12. MW: 720.9. Isolated from Streptomyces sp. Goe 14F. Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, antifungal, insecticidal and anthelmintic. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer.

[H][C@@]1(OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C\C(C)=C\C=C/[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](OC(=O)\C=C\C(O)=O)[C@H](C)[C@H](O1)C(C)C

-20°C,2°C to 8°C

UN 3462

51280000