WB analysis of various sample lysates using GTX30082 Bag1 antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX30082 Bag1 antibody. Dilution : 1:1000 Loading : 25microg per lane
Bag1 antibody
GTX30082
Overview
- SupplierGeneTex
- Product NameBag1 antibody
- Delivery Days Customer7
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:20 - 1:100. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID573
- Target nameBAG1
- Target descriptionBAG cochaperone 1
- Target synonymsBAG family molecular chaperone regulator 1; BAG-1; BCL2 associated athanogene 1; Bcl-2 associating athanogene-1 protein; BCL2-associated athanogene; Bcl-2-binding protein; glucocortoid receptor-associated protein RAP46; HAP; RAP46; receptor-associated protein, 46-KD
- HostRabbit
- IsotypeIgG
- Protein IDQ99933
- Protein NameBAG family molecular chaperone regulator 1
- Scientific DescriptionThe oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- An increase in BAG-1 by PD-L1 confers resistance to tyrosine kinase inhibitor in non-small cell lung cancer via persistent activation of ERK signalling. Lin PL et al., 2017 Nov, Eur J CancerRead more