Western blot analysis of extracts of various cell lines using BAIAP2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using BAIAP2 Polyclonal Antibody at 1:1000 dilution.
BAIAP2 Polyclonal Antibody
E-AB-60906
Product group Antibodies
Overview
- SupplierElabscience
- Product NameBAIAP2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- UNSPSC12352203