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Band3 antibody [BIII-136]

GTX11012
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetSLC4A1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Band3 antibody [BIII-136]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    BIII-136
  • Conjugate
    Unconjugated
  • Gene ID6521
  • Target name
    SLC4A1
  • Target description
    solute carrier family 4 member 1 (Diego blood group)
  • Target synonyms
    AE1; anion exchange protein 1; anion exchanger-1; band 3 anion exchanger; band 3 anion transport protein; BND3; CD233; CHC; DI; Diego blood group; EMPB3; EPB3; erythrocyte membrane protein band 3; erythroid anion exchange protein; FR; Froese blood group; RTA1A; SAO; solute carrier family 4 (anion exchanger), member 1 (Diego blood group); solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); solute carrier family 4, anion exchanger, number 1; SPH4; SW; Swann blood group; Waldner blood group; WD; WD1; WR; Wright blood group
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP02730
  • Protein Name
    Band 3 anion transport protein
  • Scientific Description
    The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kD protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Proteome alterations in erythrocytes with PIEZO1 gain-of-function mutations.
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  • Chronic lymphocytic leukemia cells bind and present the erythrocyte protein band 3: possible role as initiators of autoimmune hemolytic anemia. Galletti J et al., 2008 Sep 1, J Immunol
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