Bassianolide

Biorbyt

Bassianolide [64763-82-2]

10

64763-82-2

Research Use Only

98.00%

C48H84N4O12

909.216

Bassianolide, a cyclodepsipeptide insecticide produced by the fungal species B. bassiana and V. lecanii, demonstrates significant biological activity. Upon oral administration, it induces atony in B. mori silkworms at a concentration of 4 ppm and becomes lethal when concentrations exceed 8 ppm. Remarkably, atony in silkworm larvae can also be triggered by doses as low as 2 microg/larva. Further studies reveal that bassianolide (0.01-1 microM) specifically targets muscarinic receptors to inhibit contractions in isolated guinea pig smooth muscle tissue, elicited by acetylcholine, without affecting nicotinic receptor-induced contractions.

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-20°C

12352200