Bax(2D2), 1mg/mL [26628-22-8]

Biotium

Bax(2D2), 1mg/mL [26628-22-8]

9

Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

26628-22-8

Research Use Only

Monoclonal

2D2

1 mg/ml

BAX

BCL2 associated X, apoptosis regulator

BCL2L4, apoptosis regulator BAX, BCL2 associated X protein, BCL2-associated X protein omega, Baxdelta2(G8)-RFS protein, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, bcl-2-like protein 4, bcl2-L-4

Mouse

IgG1

Apoptosis regulator BAX

This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Human, Monkey, Mouse

-20°C

41116161