BAY 11-7082
HY-13453
Overview
- SupplierMedChem Express
- Product NameBAY 11-7082 [19542-67-7]
- Delivery Days Customer10
- CAS Number19542-67-7
- CertificationResearch Use Only
- Estimated Purity99.98
- Molecular FormulaC10H9NO2S
- Molecular Weight207.25
- Scientific DescriptionBAY 11-7082 is an IkappaBalpha phosphorylation and NF-kappaB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-alpha-induced phosphorylation of IkappaB-alpha, and decreases NF-kappaB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 ( IC 50 =0.19, 0.96 microM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1beta secretion in human and mouse cells [1] [2] [3] [4] [5] .
- SMILESN#C/C=C/S(=O)(C1=CC=C(C)C=C1)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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Product group Chemicals
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Estimated Purity≥98%
Molecular Weight207.3 Da
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Product group Chemicals
CAS Number19542-67-7
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BAY 11-7082AG-CR1-0013
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