BAY 1251152

Biorbyt

BAY 1251152 [1610358-56-9]

10

1610358-56-9

Research Use Only

C19H18F2N4O2S

404.4336

BAY 1251152 (VIP152 ) is the first potent, selective, orally available PTEFb/CDK9 inhibitor with biochemical IC50 of 9 nM and MOLM13 cell IC50 of 29 nM, displays> 50-fold selectivity against other CDKs.

S(C)(CC1C=CN=C(C=1)NC1C=C(C(=CN=1)F)C1C=CC(=CC=1OC)F)(=N)=O

12352200