BAY-218 [2162982-11-6]

TargetMol Chemicals

BAY-218 [2162982-11-6]

4

2162982-11-6

Chemical

Research Use Only

BAY-218

98%

C20H17ClFN3O3

401.82

Bindarit (AF2838)is an aryl hydrocarbon receptor (AHR) antagonist with IC50 of 39.9 nM in the human glioblastoma U87 cell line. BAY-218 inhibition of AhR stimulates pro-inflammatory monocyte and T cell responses in vitro and drives anti-tumor immune responses, leading to reduced tumor growth in vivo.

3 years

C[C@@H](CO)NC(=O)c1cc(nn(-c2cccc(F)c2)c1=O)-c1ccc(Cl)cc1

-20°C

12352200