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ProductsBack/BAY-293 [2244904-70-7]

BAY-293 [2244904-70-7]

Research Use Only
HY-114398
MedChem Express
CAS Number2244904-70-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.91
Molecular Weight448.58
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BAY-293 [2244904-70-7]
  • Delivery Days Customer
    10
  • CAS Number
    2244904-70-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.91
  • Molecular Formula
    C25H28N4O2S
  • Molecular Weight
    448.58
  • Scientific Description
    BAY-293, a valuable chemical probe, blocks RAS activation via disruption of the KRAS-SOS1 interaction with an IC50 of 21 nM. BAY-293 is a potent inhibitor of Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS[1].
  • SMILES
    COC1=C(OC)C=C(N=C(C)N=C2N[C@H](C)C3=CC(C4=C(CNC)C=CC=C4)=CS3)C2=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200