BAY 60-6583

MedChem Express

BAY 60-6583 [910487-58-0]

5

910487-58-0

Research Use Only

99.93

C19H17N5O2S

379.44

BAY 60-6583 is a potent and high-affinity agonist of adenosine A 2B receptor ( EC 50 ?= 3 nM) over A1, A2A, and A3 receptors. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with K i values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model [1] [5] .

O=C(N)CSC1=NC(N)=C(C#N)C(C2=CC=C(OCC3CC3)C=C2)=C1C#N

-20°C,2°C to 8°C

12352200