BAY-678 [675103-36-3]

MedChem Express

BAY-678 [675103-36-3]

10

675103-36-3

Research Use Only

99.59

C20H15F3N4O2

400.35

BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

N#CC1=NC=C([C@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1

-20°C,2°C to 8°C

12352200